Understanding this type of cancer
The bladder and NMIBC
The bladder is the part of the body where urine is stored. When cancer cells develop and multiply in the bladder, they can form a tumor and may spread to other parts of the body.
Non–muscle-invasive bladder cancer (NMIBC) is bladder cancer that has not spread past the lining of the bladder into the muscle. It is the most common type of bladder cancer.
- T1
- Ta
- CIS
This image shows the inside of the bladder and the different types of tumors that may grow with NMIBC.
NMIBC treatment varies based on where a person is on their journey
Bacillus Calmette-Guérin (BCG)
BCG is a common first therapy for early-stage bladder cancer that is given directly in the bladder. But sometimes, BCG therapy doesn’t work, and additional therapy is needed.
If BCG therapy isn’t working…
There are only a few approved treatment options available to try before bladder removal surgery (a procedure called a cystectomy) is needed.
Most people living with bladder cancer want to avoid having a cystectomy.
Bladder removal surgery may cause issues that:
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Affect daily life
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Change the way the body functions
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Impact the ability to pass urine or have sex
But there are reasons to feel hopeful.
ADSTILADRIN is a unique treatment that may help you keep your bladder
Important Safety Information
INDICATION
ADSTILADRIN is a treatment for adults who have all the following:
- High-risk non–muscle-invasive bladder cancer (NMIBC)
- Cancer that is not responding to Bacillus Calmette-Guérin (BCG) therapy
- Carcinoma in situ (CIS) with or without other high-grade tumors
IMPORTANT SAFETY INFORMATION
Who should not receive ADSTILADRIN?
Do not receive ADSTILADRIN if you have a sensitivity to interferon alfa or any of its components.
What is the most important information I should know about ADSTILADRIN?
Individuals who are immunosuppressed or immune-deficient should not prepare, administer, receive or come into contact with ADSTILADRIN.
What should I tell my healthcare provider?
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
What are the possible side effects of ADSTILADRIN?
The most common side effects of ADSTILADRIN include:
Urinary discharge, fatigue, bladder spasm, urgency to urinate, and blood in your urine.
These are not all the possible side effects of ADSTILADRIN. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to FDA. Visit www.FDA.gov/medwatch or call 1-800-332-10881-800-332-1088. You may also contact Ferring Pharmaceuticals at 1-888-FERRING1-888-FERRING.
What other information should I know about using ADSTILADRIN?
For 2 days following treatment, voided urine should be disinfected for 15 minutes with an equal volume of bleach before flushing.
For more important information, call 1-888-337-74641-888-337-7464.
Please see full Prescribing Information.